Blar i forfatter "Vitali, Beatrice"

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    • Liposomes-in-chitosan hydrogel boosts potential of chlorhexidine in biofilm eradication in vitro 

      Hemmingsen, Lisa Myrseth; Giordani, Barbara; Pettersen, Ann Kristin; Vitali, Beatrice; Basnet, Purusotam; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-16)
      Successful treatment of skin infections requires eradication of biofilms found in up to 90 % of all chronic wounds, causing delayed healing and increased morbidity. We hypothesized that chitosan hydrogel boosts the activity of liposomally-associated membrane active antimicrobials (MAA) and could potentially improve bacterial and biofilm eradication. Therefore, liposomes (∼300 nm) bearing chlorhexidine ...

    • Tailored anti-biofilm activity – Liposomal delivery for mimic of small antimicrobial peptide 

      Hemmingsen, Lisa Myrseth; Giordani, Barbara; Paulsen, Marianne Hagensen; Vanic, Zeljka; Flaten, Gøril Eide; Vitali, Beatrice; Basnet, Purusotam; Bayer, Annette; Strøm, Morten B.; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-13)
      The eradication of bacteria embedded in biofilms is among the most challenging obstacles in the management of chronic wounds. These biofilms are found in most chronic wounds; moreover, the biofilm-embedded bacteria are considerably less susceptible to conventional antimicrobial treatment than the planktonic bacteria. Antimicrobial peptides and their mimics are considered attractive candidates in the ...